Human NME3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NME3
Locus ID	4832
Kit Components	GA103224G1, NME3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103224G2, NME3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103224G3, NME3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002513
Synonyms	c371H6.2; DR-nm23; NDPK-C; NDPKC; NM23-H3; NM23H3
Summary	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.[UniProtKB/Swiss-Prot Function]

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