Human p75 NGF Receptor (NGFR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NGFR
Locus ID	4804
Kit Components	GA103205G1, p75 NGF Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103205G2, p75 NGF Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103205G3, p75 NGF Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002507
Synonyms	CD271; Gp80-LNGFR; p75(NTR); p75NTR; TNFRSF16
Summary	Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

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