Human NFYC activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NFYC
Locus ID	4802
Kit Components	GA103203G1, NFYC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103203G2, NFYC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103203G3, NFYC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142587, NM_001142588, NM_001142589, NM_001142590, NM_001308114, NM_001308115, NM_014223
Synonyms	CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC
Summary	This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

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