Human Neogenin (NEO1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEO1
Locus ID	4756
Kit Components	GA103172G1, Neogenin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103172G2, Neogenin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103172G3, Neogenin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001172623, NM_001172624, NM_002499
Synonyms	IGDCC2; NGN; NTN1R2
Summary	This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

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