Human Melatonin Receptor 1A (MTNR1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTNR1A
Locus ID	4543
Kit Components	GA103026G1, Melatonin Receptor 1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103026G2, Melatonin Receptor 1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103026G3, Melatonin Receptor 1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005958
Synonyms	MEL-1A-R; MT1
Summary	This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]

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