Human LMO2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LMO2
Locus ID	4005
Kit Components	GA102714G1, LMO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102714G2, LMO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102714G3, LMO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142315, NM_001142316, NM_005574
Synonyms	RBTN2; RBTNL1; RHOM2; TTG2
Summary	LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]

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