Human LGALS3BP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LGALS3BP
Locus ID	3959
Kit Components	GA102684G1, LGALS3BP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102684G2, LGALS3BP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102684G3, LGALS3BP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005567
Synonyms	90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
Summary	The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

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