Human LCK activation kit by CRISPRa

CAT#: GA102666

LCK CRISPRa kit - CRISPR gene activation of human LCK proto-oncogene, Src family tyrosine kinase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal LCK Antibody (N-term)
    • 400 ul

CNY 6,160.00


LCK (Myc-DDK-tagged)-Human lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 1
    • 10 ug

CNY 5,688.00


Rabbit anti p56-LCK (LSK) Polyclonal Antibody
    • 100 ug

CNY 4,037.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol LCK
Locus ID 3932
Kit Components

GA102666G1, LCK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102666G2, LCK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102666G3, LCK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001042771, NM_001330468, NM_005356
Synonyms IMD22; LSK; p56lck; pp58lck; YT16
Summary This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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