Human Cytokeratin 5 (KRT5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KRT5
Locus ID	3852
Kit Components	GA102614G1, Cytokeratin 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102614G2, Cytokeratin 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102614G3, Cytokeratin 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000424
Synonyms	CK5; DDD; DDD1; EBS2; K5; KRT5A
Summary	The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

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