Human KCNJ1 activation kit by CRISPRa

CAT#: GA102534

KCNJ1 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-KCNJ1 Antibody
    • 100 ul

CNY 5,250.00


Lenti ORF particles, KCNJ1 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 1 (KCNJ1), transcript variant rom-k1, 200ul, >10^7 TU/mL
    • 200 ul

CNY 8,930.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol KCNJ1
Locus ID 3758
Kit Components

GA102534G1, KCNJ1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102534G2, KCNJ1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102534G3, KCNJ1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000220, NM_153764, NM_153765, NM_153766, NM_153767
Synonyms KIR1.1; ROMK; ROMK1
Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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