Human gamma Catenin (JUP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JUP
Locus ID	3728
Kit Components	GA102509G1, gamma Catenin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102509G2, gamma Catenin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102509G3, gamma Catenin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002230, NM_021991, NM_001352773, NM_001352774, NM_001352775, NM_001352776, NM_001352777
Synonyms	ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
Summary	This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]

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