Human Integrin beta 8 (ITGB8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITGB8
Locus ID	3696
Kit Components	GA102485G1, Integrin beta 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102485G2, Integrin beta 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102485G3, Integrin beta 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002214
Synonyms	integrin, beta 8
Summary	This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

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