Human Integrin alpha 5 (ITGA5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITGA5
Locus ID	3678
Kit Components	GA102468G1, Integrin alpha 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102468G2, Integrin alpha 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102468G3, Integrin alpha 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002205
Synonyms	CD49e; FNRA; VLA-5; VLA5A
Summary	The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

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