Human Integrin Linked Kinase (ILK) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ILK
Locus ID	3611
Kit Components	GA102417G1, Integrin Linked Kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102417G2, Integrin Linked Kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102417G3, Integrin Linked Kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001014794, NM_001014795, NM_001278441, NM_001278442, NM_004517
Synonyms	HEL-S-28; ILK-1; ILK-2; P59; p59ILK
Summary	This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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