Human Amylin (IAPP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IAPP
Locus ID	3375
Kit Components	GA102295G1, Amylin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102295G2, Amylin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102295G3, Amylin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000415, NM_001329201
Synonyms	DAP; IAP
Summary	This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]

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