Human beta glucuronidase (GUSB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GUSB
Locus ID	2990
Kit Components	GA102029G1, beta glucuronidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102029G2, beta glucuronidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102029G3, beta glucuronidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000181, NM_001284290, NM_001293104, NM_001293105, NR_120531
Synonyms	BG; MPS7
Summary	This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014]

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