Human MSH6 activation kit by CRISPRa

CAT#: GA102001

MSH6 CRISPRa kit - CRISPR gene activation of human mutS homolog 6



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
MSH6 mouse monoclonal antibody,clone OTI5D1
    • 100 ul

CNY 1,999.00
CNY 2,700.00


MSH6 (Myc-DDK-tagged)-Human mutS homolog 6 (E. coli) (MSH6)
    • 10 ug

CNY 13,960.00


MSH6 mouse monoclonal antibody,clone OTI5D1
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MSH6
Locus ID 2956
Kit Components

GA102001G1, MSH6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102001G2, MSH6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102001G3, MSH6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000179, NM_001281492, NM_001281493, NM_001281494
Synonyms GTBP; GTMBP; HNPCC5; HSAP; p160
Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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