Human Glutathione S Transferase theta 1 (GSTT1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSTT1
Locus ID	2952
Kit Components	GA101998G1, Glutathione S Transferase theta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101998G2, Glutathione S Transferase theta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101998G3, Glutathione S Transferase theta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000853, NM_001293807, NM_001293808, NM_001293809, NM_001293810, NM_001293811, NM_001293812, NM_001293813, NM_001293814
Synonyms	glutathione S-transferase theta 1
Summary	The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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