Human GRIK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRIK1
Locus ID	2897
Kit Components	GA101953G1, GRIK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101953G2, GRIK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101953G3, GRIK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000830, NM_175611, NM_001320616, NM_001320618, NM_001320621, NM_001320630, NM_001330993, NM_001330994
Synonyms	EAA3; EEA3; GLR5; GluK1; GLUR5
Summary	Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.