Human GLRB activation kit by CRISPRa

CAT#: GA101830

GLRB CRISPRa kit - CRISPR gene activation of human glycine receptor beta



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit polyclonal anti-GLRB antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


Lenti ORF particles, GLRB (Myc-DDK-tagged)-Human glycine receptor, beta (GLRB), transcript variant 3, 200ul, >10^7 TU/mL
    • 200 ul

CNY 8,170.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol GLRB
Locus ID 2743
Kit Components

GA101830G1, GLRB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101830G2, GLRB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101830G3, GLRB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000824, NM_001166060, NM_001166061
Synonyms HKPX2
Summary This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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