Human GLB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GLB1
Locus ID	2720
Kit Components	GA101816G1, GLB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101816G2, GLB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101816G3, GLB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000404, NM_001079811, NM_001135602, NM_001317040
Synonyms	EBP; ELNR1; MPS4B
Summary	This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. [provided by RefSeq, Nov 2015]

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