Human Frataxin (FXN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FXN
Locus ID	2395
Kit Components	GA101655G1, Frataxin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101655G2, Frataxin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101655G3, Frataxin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000144, NM_001161706, NM_181425
Synonyms	CyaY; FA; FARR; FRDA; X25
Summary	This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.