Human FPR3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FPR3
Locus ID	2359
Kit Components	GA101654G1, FPR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101654G2, FPR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101654G3, FPR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002030
Synonyms	FML2_HUMAN; FMLP-R-II; FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I
Summary	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]

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