Human EXTL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXTL2
Locus ID	2135
Kit Components	GA101488G1, EXTL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101488G2, EXTL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101488G3, EXTL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033025, NM_001261440, NM_001261441, NM_001261442, NM_001439, NR_048570
Synonyms	EXTR2
Summary	Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.[UniProtKB/Swiss-Prot Function]

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