Human Estrogen Related Receptor alpha (ESRRA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ESRRA
Locus ID	2101
Kit Components	GA101463G1, Estrogen Related Receptor alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101463G2, Estrogen Related Receptor alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101463G3, Estrogen Related Receptor alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282450, NM_001282451, NM_004451
Synonyms	ERR1; ERRa; ERRalpha; ESRL1; NR3B1
Summary	The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019]

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