Human XPB (ERCC3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERCC3
Locus ID	2071
Kit Components	GA101448G1, XPB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101448G2, XPB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101448G3, XPB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000122, NM_001303416, NM_001303418
Synonyms	BTF2; GTF2H; RAD25; TFIIH; TTD2; XPB
Summary	This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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