Human MARK2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MARK2
Locus ID	2011
Kit Components	GA101394G1, MARK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101394G2, MARK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101394G3, MARK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039468, NM_001039469, NM_001163296, NM_001163297, NM_004954, NM_017490
Synonyms	ELKL motif kinase 1; EMK1; MAP/microtubule affinity-regulating kinase 2; MGC99619; PAR-1; Par1b; protein-serine/threonine kinase; Ser/Thr protein kinase PAR-1B; serine/threonine kinase
Summary	This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

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