Human ECT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ECT2
Locus ID	1894
Kit Components	GA101322G1, ECT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101322G2, ECT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101322G3, ECT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001258315, NM_001258316, NM_018098, NM_001349094, NM_001349095, NM_001349096, NM_001349097, NM_001349098, NM_001349099, NM_001349100, NM_001349101, NM_001349102, NM_001349103, NM_001349104
Synonyms	ARHGEF31
Summary	The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]

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