Human Dystrobrevin beta (DTNB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DTNB
Locus ID	1838
Kit Components	GA101288G1, Dystrobrevin beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101288G2, Dystrobrevin beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101288G3, Dystrobrevin beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256303, NM_001256304, NM_001256308, NM_021907, NM_033147, NM_033148, NM_183360, NM_183361, NM_001320932, NM_001320933, NM_001320934, NM_001320935, NM_001320936, NM_001320937, NM_001351381, NM_001351382, NM_001351383, NM_001351384, NM_001351385, NM_001351386, NM_001351387, NM_001351388, NM_001351389, NM_001351390, NM_001351391, NM_001351392, NM_001351393, NM_001351394, NM_001351395, NR_147180
Summary	This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. [provided by RefSeq, Mar 2016]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.