Human Desmin (DES) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DES
Locus ID	1674
Kit Components	GA101184G1, Desmin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101184G2, Desmin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101184G3, Desmin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001927
Synonyms	CSM1; CSM2; LGMD2R
Summary	This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

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