Human DDB2 activation kit by CRISPRa

CAT#: GA101158

DDB2 CRISPRa kit - CRISPR gene activation of human damage specific DNA binding protein 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
DDB2 mouse monoclonal antibody,clone OTI2E12
    • 100 ul

CNY 1,999.00
CNY 2,700.00


DDB2 (Myc-DDK-tagged)-Human damage-specific DNA binding protein 2, 48kDa (DDB2)
    • 10 ug

CNY 3,656.00
CNY 5,320.00


DDB2 mouse monoclonal antibody,clone OTI2E12
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DDB2
Locus ID 1643
Kit Components

GA101158G1, DDB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101158G2, DDB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101158G3, DDB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000107, NM_001300734
Synonyms DDBB; UV-DDB2; XPE
Summary This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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