Human D Amino Acid Oxidase (DAO) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DAO
Locus ID	1610
Kit Components	GA101134G1, D Amino Acid Oxidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101134G2, D Amino Acid Oxidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101134G3, D Amino Acid Oxidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001917
Synonyms	DAAO; DAMOX; OXDA
Summary	This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]

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