Human DGKB activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DGKB
Locus ID	1607
Kit Components	GA101131G1, DGKB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101131G2, DGKB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101131G3, DGKB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004080, NM_145695, NM_001350705, NM_001350706, NM_001350707, NM_001350708, NM_001350709, NM_001350711, NM_001350712, NM_001350714, NM_001350715, NM_001350716, NM_001350717, NM_001350718, NM_001350719, NM_001350720, NM_001350721, NM_001350722, NM_001350723, NM_001350724
Synonyms	DAGK2; DGK; DGK-BETA
Summary	Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]

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