Human CYP3A7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CYP3A7
Locus ID	1551
Kit Components	GA101095G1, CYP3A7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101095G2, CYP3A7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101095G3, CYP3A7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000765
Synonyms	CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]

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