Human Cytochrome P450 1A2 (CYP1A2) activation kit by CRISPRa

CAT#: GA101091

CYP1A2 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 1 subfamily A member 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-CYP1A2 (Cytochrome P450 1A2) mouse monoclonal antibody, clone OTI6E2 (formerly 6E2)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


CYP1A2 (Myc-DDK-tagged)-Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2)
    • 10 ug

CNY 3,840.00
CNY 3,990.00


CYP1A2 biotinylated mouse monoclonal detection antibody, validated for ELISA assays
    • 50 ug

CNY 2,700.00
CNY 3,790.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CYP1A2
Locus ID 1544
Kit Components

GA101091G1, Cytochrome P450 1A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101091G2, Cytochrome P450 1A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101091G3, Cytochrome P450 1A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000761
Synonyms CP12; P3-450; P450(PA)
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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