Human Casein Kinase 1 alpha (CSNK1A1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CSNK1A1
Locus ID	1452
Kit Components	GA101023G1, Casein Kinase 1 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101023G2, Casein Kinase 1 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101023G3, Casein Kinase 1 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025105, NM_001271741, NM_001271742, NM_001892
Synonyms	CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975
Summary	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).[UniProtKB/Swiss-Prot Function]

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