Human Collagen IV alpha 6 (COL4A6) activation kit by CRISPRa

CAT#: GA100902

COL4A6 CRISPRa kit - CRISPR gene activation of human collagen type IV alpha 6 chain



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal Collagen IV a6 antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


COL4A6 (Myc-DDK-tagged)-Human collagen, type IV, alpha 6 (COL4A6), transcript variant A
    • 10 ug

CNY 11,368.00


Rabbit Polyclonal Anti-COL4A6 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol COL4A6
Locus ID 1288
Kit Components

GA100902G1, Collagen IV alpha 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100902G2, Collagen IV alpha 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100902G3, Collagen IV alpha 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001287758, NM_001287759, NM_001287760, NM_001847, NM_033641
Synonyms CXDELq22.3; DELXq22.3; DFNX6
Summary This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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