Human CNGB1 activation kit by CRISPRa

CAT#: GA100878

CNGB1 CRISPRa kit - CRISPR gene activation of human cyclic nucleotide gated channel subunit beta 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
CNGB1 (Myc-DDK-tagged)-Human cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant 2
    • 10 ug

CNY 3,600.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CNGB1
Locus ID 1258
Kit Components

GA100878G1, CNGB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100878G2, CNGB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100878G3, CNGB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001135639, NM_001286130, NM_001297
Synonyms CNCG2; CNCG3L; CNCG4; CNG4; CNGB1B; GAR1; GARP; GARP2; RCNC2; RCNCb; RCNCbeta; RP45
Summary In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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