Human CLCN2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLCN2
Locus ID	1181
Kit Components	GA100843G1, CLCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100843G2, CLCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100843G3, CLCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001171087, NM_001171088, NM_001171089, NM_004366
Synonyms	CIC-2; clC-2; CLC2; ECA2; ECA3; EGI3; EGI11; EGMA; EJM6; EJM8; LKPAT
Summary	This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

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