Human BTK activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BTK
Locus ID	695
Kit Components	GA100484G1, BTK gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100484G2, BTK gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100484G3, BTK gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000061, NM_001287344, NM_001287345
Synonyms	AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Summary	The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

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