Human Amphiregulin (AREG) activation kit by CRISPRa

CAT#: GA100268

AREG CRISPRa kit - CRISPR gene activation of human amphiregulin



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

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AREG Rabbit polyclonal Antibody
    • 100 ul

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AREG (Myc-DDK-tagged)-Human amphiregulin (AREG)
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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol AREG
Locus ID 374
Kit Components

GA100268G1, Amphiregulin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100268G2, Amphiregulin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100268G3, Amphiregulin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001657
Synonyms AR; AREGB; CRDGF; SDGF
Summary The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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