Human APBB2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	APBB2
Locus ID	323
Kit Components	GA100224G1, APBB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100224G2, APBB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100224G3, APBB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001166050, NM_001166051, NM_001166052, NM_001166053, NM_001166054, NM_004307, NM_173075, NM_001330656, NM_001330658
Synonyms	FE65L; FE65L1
Summary	The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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