Human Acyloxyacyl Hydrolase (AOAH) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AOAH
Locus ID	313
Kit Components	GA100215G1, Acyloxyacyl Hydrolase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100215G2, Acyloxyacyl Hydrolase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100215G3, Acyloxyacyl Hydrolase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001177506, NM_001177507, NM_001637
Summary	This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]

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