Human Jagged1 (JAG1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JAG1
Locus ID	182
Kit Components	GA100128G1, Jagged1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100128G2, Jagged1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100128G3, Jagged1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000214
Synonyms	AGS; AHD; AWS; CD339; HJ1; JAGL1
Summary	The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019]

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