Human alpha smooth muscle Actin (ACTA2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ACTA2
Locus ID	59
Kit Components	GA100046G1, alpha smooth muscle Actin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100046G2, alpha smooth muscle Actin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100046G3, alpha smooth muscle Actin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001141945, NM_001320855, NM_001613
Synonyms	AAT6; ACTSA; MYMY5
Summary	This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]

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