Zfand5 (NM_001106356) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR213513L3V
- LentiORF®
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Lenti ORF particles, Zfand5 (Myc-DDK-tagged ORF) - Rat zinc finger, AN1-type domain 5 (Zfand5), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Zfand5 (NM_001106356) Rat Tagged ORF Clone Lentiviral Particle |
Synonyms | Zfp216 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001106356 |
ORF Size | 339 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR213513).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001106356.1, NP_001099826.1 |
RefSeq Size | 2755 bp |
RefSeq ORF | 342 bp |
Locus ID | 293960 |
Gene Summary | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation (By similarity).[UniProtKB/Swiss-Prot Function] |
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