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Uba1 (NM_001014080) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR211933L3V
- LentiORF®
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Lenti ORF particles, Uba1 (Myc-DDK-tagged ORF) - Rat ubiquitin-like modifier activating enzyme 1 (Uba1), 200ul, >10^7 TU/mL
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CNY 18,896.00
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Specifications
| Product Data | |
| Product Name | Uba1 (NM_001014080) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Ube1x |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001014080 |
| ORF Size | 3174 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR211933).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001014080.1, NP_001014102.1 |
| RefSeq Size | 3618 bp |
| RefSeq ORF | 3177 bp |
| Locus ID | 314432 |
| Gene Summary | Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites.[UniProtKB/Swiss-Prot Function] |
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