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Sh3rf2 (NM_001034187) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR210595L3V
- LentiORF®
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Lenti ORF particles, Sh3rf2 (Myc-DDK-tagged ORF) - Rat SH3 domain containing ring finger 2 (Sh3rf2), 200ul, >10^7 TU/mL
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CNY 12,189.00
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Specifications
| Product Data | |
| Product Name | Sh3rf2 (NM_001034187) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Posh2; Ppp1r39 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001034187 |
| ORF Size | 2205 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR210595).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001034187.1, NP_001029359.1 |
| RefSeq Size | 2497 bp |
| RefSeq ORF | 2208 bp |
| Locus ID | 307472 |
| Gene Summary | Has E3 ubiquitin-protein ligase activity. Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169). Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation. Inhibits PPP1CA phosphatase activity (By similarity).[UniProtKB/Swiss-Prot Function] |
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