United States
Germany
Japan
United Kingdom
China
Sh3rf2 (NM_001034187) Rat Untagged Clone
CAT＃: RN210595
Sh3rf2 (untagged ORF) - Rat SH3 domain containing ring finger 2 (Sh3rf2), (10 ug)
CNY 9,500.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Posh2; Ppp1r39 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN210595 representing NM_001034187
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATGATTTGACGTTACTTGATCTCCTGGAGTGCCCCGTGTGCTTTGAAAAGCTCGATGTTACAGCCA AAGTTCTCCCCTGCCAGCACACCTTCTGCAAACCATGTCTACAGCGGATTTTCAAGGCCCACAAGGAGCT GAGGTGCCCGGAATGCAGGACCCTGGTGTTCTGCAGCATCGAGGCTCTGCCAGCCAACCTGTTGCTGGTG CGTCTGCTGGATGGAGTGCGCTCCGGGCACAACTCGTGGAGAGGAGGCTCCTTTCGAAGGCCTCGAATAC TAACCTTGCAGGACAACAGGAAAGCCAAGAGCAGCCCCAGAAGTCTGCAGGCCAGCCCTTTCCGGCTGGG GCCCACTGTCAGGATCCACATGGATGGGGTGCCTCGAGCCAAGGCCTTGTGCAACTACAGAGGGAAGAAT CCTGGCGACCTGAAGTTTAATAAAGGAGATGTCATCCTCCTTCAGAGACAGCTTGATGAGAACTGGTACC AGGGGGAGATCAATGGGGTCAGTGGGTTCTTCCCAGCCAGCTCTGTGGAAGTCATCAAGCAGCTGCCCCA GCCACCCCCTCTCTGCAGAGCCCTCTACAACTTTGACCTTCGAGATAAGGATAAGAGTGAGAACCAGGAT TGCCTGACCTTCCTCAAGGATGATGTCATCACAGTGATCAGCCGAGTAGACGAGAACTGGGCAGAAGGAA AACTCGGAGATAAAGTAGGCATCTTCCCCATCTTGTTTGTAGAGCCAAACCTCTCTGCAAGACACCTCCT AGAGAAGAGCAAAGGGCATCAGTTATCACGCACAAAACATCTGTCCCTGATGTCCTCACCATCTAGAGGC AAAGCAACCAACACATCCACTCTCCGCAAGAGCCCAGGGTCCAGGAGGAAAGGATCCGGGCAGTTCGCCA TGACTACAGCTTTGAATACACTCAACCGCATGGTCCATTCTCCTGAAGGTCACCAGATGGTGGAAATCAG CACCCCAGTGCTCATCAGCTCTACCAGTCCCTCTATGCTCACCCAGCATGGGGACAGGGCCGATTTCCCT GCCAGCTCTGCAGGACAGGTCAGCACTTCTCACCCTGCTCCTGCCTCCCCAGGACATTCCACAGCCATGG TCAGTGTGCCCAGCTCCCAGCAACACCTCTCAACGAACATGTTTGTAGCCCTGCACACTTACTCAGCCCA GGGACCTGAAGAGCTGGACCTGAAGAAGGGAGAAGGTATCAGGGTTCTGGGCAAGAATCAGGATGGCTGG CTGAGGGGCGTCTCCTTAGTCACTGGACGAACTGGCATCTTTCCAAGCGACTATGTCATCCCCGTTTTCA GCTCAACAGCTAGAAAGACATCTAGTTTTCCTGATTCCCGGCACCCCACTGTCTGCACCACATGGGCGTT ATCCACCTCCTCTGTGTCCTCCCAGGGTAGCTTTTCAGAAGGCGATCCCCGGCAAAGTGGACCCTTCAGA TCTGTCTTTGTGCCCACTGCCGTTAACCCTCCAAGGAGCACATCTGGCCCTGGGACTTCTGGACAAGGGT CTCTTAGGAAAGTGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCAGTTCAATCAGGGATCCC CACTTTCATGGTGGGCTCCCTCAGGTGCAGTCCTGCCATGGTGATCCGGCCTCAGAAGTTCCAGTTTTAT CAGCCACAGGGGATGACCCCTTCCCCAACACCCATAATGGTGGAGATAGGGTCTAAATCTATTTCCACTG GGGAGCCTGCCCTGACCTGCATCAACAGAGGTGGCAAGACCAGGACCCACTCCGCAGGCAATTCCATCAT CATGGAAGGCAAAGAAACACCCATCAAGAGTGAGCCTCCACCCAAGCCGCCTGCGTCTGCACCACCCTCC ATCCTCGTGAAACCAGAAAATTCAAAAAATGGTATTGAAAAGCAAGTCAAAACCGTGAGATTTCAGAATT ACAGCCCTCCGCCCACCAAACACTCTGCCTCCGGTCCCACCTCTGGAAAGCATGAACAGCCAGCCACCTT GAAGGGGTCCCAACCTGAAGCAGTCTCCTCAGAAGGAGAGATGACCATTCTATTTGCCCACCGAAGTGGC TGCCACTCCGGGCAACAGACAGACCTTCGGAGAAAGTCAGCCTTTAGCAAGACCACACCCCCAGTGTCCA CTGCTTCAGTCTCACAGACCTTATTTCCCAGCAAATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001034187 |
| Insert Size | 2208 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001034187.1, NP_001029359.1 |
| RefSeq Size | 2497 bp |
| RefSeq ORF | 2208 bp |
| Locus ID | 307472 |
| UniProt ID | Q498M5 |
| Gene Summary | Has E3 ubiquitin-protein ligase activity. Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169). Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation. Inhibits PPP1CA phosphatase activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR210595 | Sh3rf2 (Myc-DDK-tagged ORF) - Rat SH3 domain containing ring finger 2 (Sh3rf2), (10 ug) |
CNY 9,500.00 |
|
| RR210595L3 | Lenti ORF clone of Sh3rf2 (Myc-DDK-tagged ORF) - Rat SH3 domain containing ring finger 2 (Sh3rf2), (10 ug) |
CNY 11,210.00 |
|
| RR210595L4 | Lenti ORF clone of Sh3rf2 (mGFP-tagged ORF) - Rat SH3 domain containing ring finger 2 (Sh3rf2), (10 ug) |
CNY 12,350.00 |
