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Neuro D4 (DPF1) (NM_004647) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC229181L3V
- LentiORF®
-
Lenti ORF particles, DPF1 (Myc-DDK tagged) - Human D4, zinc and double PHD fingers family 1 (DPF1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
| Product Data | |
| Product Name | Neuro D4 (DPF1) (NM_004647) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BAF45b; NEUD4; neuro-d4 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_004647 |
| ORF Size | 1140 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC229181).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004647.2, NP_004638.2 |
| RefSeq ORF | 1062 bp |
| Locus ID | 8193 |
| Domains | PHD |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 42.3 kDa |
| Gene Summary | May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).[UniProtKB/Swiss-Prot Function] |
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